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Retrieved from: Torkan, B., Mousavi, M., Dehghani, S., et al
Group III: reserpine + low dose of semaglutide (Res + LD of Sema group), Group IV: reserpine + intermediate dose of semaglutide (Res + ID of Sema group), and Group V: reserpine + high dose of semaglutide (Res + HD of Sema): reserpine (1 mg/kg/day) was subcutaneously administered into rats for 3 successive days, then they were daily injected with intraperitoneal low (5 nmol/kg), intermediate (10 nmol/kg) (Yang et al
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However, more participants discontinued treatment with tirzepatide 10 mg (OR 2.39 [95% CI 1.02, 5.59], I 2 0%) and 15 mg (OR 3.64 [95% CI 1.51, 8.78], I 2 13%) when compared with placebo (ESM Table 3)
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