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Patients had improved outcomes after ST-elevation myocardial infarction (STEMI) and when living with coronary plaque when using glucagon-like peptide-1 (GLP-1) receptor agonists according to posters presented during the 1,2 These results encourage the use of GLP-1s in this area, improving survival for patients living with these conditions

doi: 10.1371/journal.pone.0054040 134 MertensK

30 Among the pathways activated by IR and IGF-1R signaling are the RASRAFMEK1/2extracellular signal-regulated kinase (ERK)-1/2 pathway 34 and the phosphatidylinositol-3-kinase (PI3K)AKTmammalian target of rapamycin (mTOR) pathway, two fundamental pathways for tumor cell proliferation and survival (Figure 2)