When someone has already improved their sleep, nutrition, and hydration and still feels depleted, the direct delivery route can be a practical option, particularly for individuals whose digestive systems absorb nutrients inconsistently
Not for use in therapeutic or diagnostic procedures
Dietary recommendations include: Eating smaller, more frequent meals rather than large portions, which can overwhelm the slowed digestive system Increasing dietary fibre gradually through fruits, vegetables, whole grains, and legumes to support regular bowel movements and potentially benefit diverticular disease Maintaining adequate hydration aim for 6-8 glasses of water daily, particularly important if experiencing diarrhoea or constipation Limiting high-fat, fried, and spicy foods that may exacerbate nausea and delayed gastric emptying Avoiding carbonated beverages if experiencing bloating or discomfort Eating slowly and chewing thoroughly to aid digestion Lifestyle measures that support gastrointestinal health include regular physical activity, which promotes gut motility and can help prevent constipation

Targeting ETC CI enhances 5FU response and extends survival The ultimate goal of better understanding mechanisms promoting 5FU tolerance is to allow us to design rational treatment combinations that are more effective than the current standard of care
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