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[9] [12] Tirzepatide (as Zepbound) is indicated, alongside a reduced-calorie diet and increased physical activity, for long-term weight reduction in adults with obesity or overweight with at least one weight-related comorbidity
Furthermore, the rate of rebound weight gain following the cessation of GLP-1R agonists, as well as the implementation of future strategies to avoid this phenomenon, are other issues that need to be thoroughly addressed in future studies [65]
This small cohort cannot establish safety or optimal dosing
Eligible patients in Maryland and Delaware may receive in-person or telehealth care based on their location and clinical needs Some patients notice changes in appetite during the first few doses, while others require gradual dose escalation before experiencing a meaningful effect
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