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The exact human half-life has not been fully confirmed, but current estimates suggest it may remain active for only a few hours

Aging-related circulating metabolites regulate EC functions Arachidonic acid (AA), a membrane phospholipid component, is metabolized by cyclooxygenases (COXs), lipoxygenases (LOXs), and cytochrome P450 enzymes to generate eicosanoids including prostaglandins (PGs), thromboxanes (TXs), leukotrienes, and epoxyeicosatrienoic acids (EETs) [173, 174]

Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor ffar1

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