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ROS can modify sperm proteins, leading to structural changes that impair motility, metabolic processes, and the sperms ability to bind to the oocyte

GST class-alpha member 1

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of India, Krishi Bhavan

Additionally, NSW affects methylation of immune-modulatory genes and human endogenous retroviral elements such as ERVFRD-1, HERV-L, and HERV-P, indicating combined effects of circadian and metabolic stressors on immune epigenetic regulation 234