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Meta-analyses on gray and white matter changes in T2DM patients with cognitive impairment have concluded that T2DM impairs cognitive function by affecting specific brain structures (Potenza et al., 2021)

249 This activation promotes catabolic processes that generate energy and, concurrently, inhibits mTORC1, halting energy-consuming processes such as gluconeogenesis, lipid synthesis, and protein synthesis

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It is one of the most pressing problems for which people visit the medical practitioners worldwide

Dietary sources include red meat, dairy, and fish, though vegans and those with low natural production may benefit from supplementation