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Leave it alone and let the soreness subside naturally
LY3437943 (Retatrutide): discovery to clinical proof of concept (triple GLP-1/GIP/glucagon agonist, preclinical mechanism) Nature Reviews Endocrinology (2024) Multi-receptor agonists for metabolic disease (mechanism of GLP-1/GIP/glucagon co-activation) Diabetes Care (2024) Incretin-based therapies: GLP-1, GIP, and glucagon receptor pharmacology (metabolic pathways, energy expenditure) NEJM (2023) Supplementary Material Jastreboff et al
Weeks 4-8 typically bring more noticeable functional gains
It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals
Vegans and vegetarians may require supplementation, as plant-based foods contain negligible B12 unless fortified
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