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Holocarboxylase Synthetase Deficiency Deficiency in holocarboxylase synthetase is an autosomal recessive disorder that results in multiple carboxylase deficiency
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Moreover, iron metabolism-associated genes, including FTH, TFR1, and SLC11A2, are regulated by hypoxia-responsive elements (HREs) in the promotor region (Li et al., 2019)
There was also a tendency for increased levels of glutamine (Fig
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