Among patients who switched to a different GLP-1 RA medication, they primarily switched to semaglutide labeled for T2D (24.5%) or to tirzepatide labeled for T2D (14.9%)
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Pediatric exclusivity, worth six months at $3 billion in annual revenues, is worth considerably less if Medicare has negotiated a 30% to 40% price reduction for the final years of the drugs exclusivity
So not only does excess weight lead to insulin resistance, which increases the risk of conditions like diabetes and heart disease, but inflammation as well, which can play a role in the uncontrolled growth of cells that lead to tumors, all of which can drastically lower our life expectancy