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Oral GLP-1 weight loss medication Orfoglipron (Eli Lilly) is nearing an FDA decision with available expect mid-2026 Clinical trials show meaningful results: 12-16% 1,2 average weight loss, which is slightly less than injectables Side effects are similar: mostly gastrointestinal, such as nausea or diarrhea, typically improving over 23 months
During this one-on-one appointment, youll have the opportunity to ask questions about the treatment, undergo a thorough evaluation, and discuss your medical and lifestyle history
While generally mild and reversible, physicians will be watching the safety data closely
BMC Endocrine Disorders, 23 , 190 (2023)
By alleviating chronic systemic inflammation, GLP-1RAs may help prevent the progression of HF and adverse cardiovascular events
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