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In both men and women, mean values of SFA, omega-6 PUFA, total iron, omega-3 PUFA, vitamin C, vitamin E, selenium, beta-carotene, and zinc intake increased according to the increasing sex-specific OBS quartile

Seino Y et al

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However, owing to the lack of consideration for brain capillary binding or sequestration, the reliability of these results regarding brain uptake pharmacokinetics has been questioned [21] as well as whether results could be translated into humans