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2019;5(7):e02162
Most people's digestive systems adapt over time, but proactive strategies can minimize discomfort during the adjustment period
However, they typically will last for several days and up to a week, slowly improving
Patients will maintain the standard 0.25mg dose for the first four weeks before increasing to 0.5mg in the fifth week, followed by 1mg for the subsequent increase
The dosage is increased in 2.5 mg increments every 4 weeks until reaching the maximum tolerated dose
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