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Their major mechanisms of action are slowing of gastric emptying, hunger suppression, increased insulin and decreased glucagon secretion from the pancreas
G.FasanoR.MalerbaE.PreteM.et al
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Treatment effects based on data obtained from treatment completers A frequently used method to estimate the effect in randomized trials is through restricting the analysis set to comprising only data from patients who continue the randomized treatment until the scheduled end-of-treatment visit (i.e., treatment completers)
Ahmann AJ, Capehorn M, Charpentier G, et al Efficacy and safety of once-weekly semaglutide versus exenatide ER in subjects with type 2 diabetes (SUSTAIN 3): a 56-week, open-label, randomized clinical trial
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