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The drugmaker said it had in recent months intensified efforts to align prices across developed countries, especially in Europe. This rebalancing may be difficult, but it means the prices for medicines paid by governments and health systems need to increase in other developed markets like Europe in order to make them lower in the US, the company said in the statement

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theyre entirely different chemical formulations with their own unique risks and unknowns

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With an investigational drug such as retatrutide, the safest wording is that responses in trials may not predict an individual result