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Among the three FDA-approved medications, weight loss was greatest (up to 17.8% through 72 weeks) with tirzepatide 15 mg once weekly, followed by semaglutide 2.4 mg once weekly (up to 13.9% through 68 weeks) and liraglutide (up to 5.8% through 26 weeks)
This supports ongoing pharmacovigilance and patient safety
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The callose content was quantified using aniline blue staining, followed by fluorometric measurement with an F-7000 fluorescence spectrophotometer (Hitachi High-Tech Corporation, Tokyo, Japan)
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