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Clin Pharmacokinet 60:13351348 McGuire DK, Busui RP, Deanfield J et al (2023) Effects of oral semaglutide on cardiovascular outcomes in individuals with type 2 diabetes and established atherosclerotic cardiovascular disease and/or chronic kidney disease: design and baseline characteristics of SOUL, a randomized trial

Purity indicates how much of the sample is the actual peptide, while identity confirms it is the correct molecule and not a cheaper look-alike

In December 2025, the FDA also approved an oral version of Wegovy a once-daily pill that must be taken on an empty stomach in the morning, with a waiting period before eating or drinking

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It has 94% amino acid sequence homology to native GLP-1, and is structurally similar to liraglutide, a once-daily GLP-1 receptor agonist [21]