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Am J Physiology-Endocrinology Metabolism 312(3):E224E233 Tomiyama T, Shimada H (2020) APP Osaka mutation in familial Alzheimers diseaseIts discovery, phenotypes, and mechanism of recessive inheritance

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Clinical studies and user reviews of tirzepatide highlight significant weight loss, better blood sugar control, and improved quality of life, though gastrointestinal side effects are common