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Tirzepatide reduces appetite, energy intake, and fat mass in people with type 2 diabetes
Similarly, GLP-1R agonists are candidate therapies for AD due to their role in modulating neuroinflammation and -amyloid accumulation
Mitigates risk of cardiovascular complications
Eligibility is restricted to adults with a BMI of at least 35 kg/m and at least one weight-related comorbidity, or a BMI of 40 or above, who have not achieved meaningful weight loss through nutritional management, and who are under specialist supervision with a lifestyle programme
Unlike injectables, pills avoid sterile bottlenecks
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