According to Table 1, comprehensive experimental and observational studies reveal that GLP-1RAs do not elevate overall cancer risk, while preclinical investigations have demonstrated multiple anti-tumor mechanisms, including proliferation inhibition, apoptosis induction, and metastasis suppression
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Some prescribe GLP-1s to treat binge eating disorder a serious condition involving rapidly eating large meals with a loss of control, followed by feelings of intense shame despite these drugs not being approved for that purpose, says Elliott