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Despite sharing this end goal, they belong to two structurally and pharmacologically distinct families, which is exactly why they are so often compared

While increasing rifampin dosing was shown to improve mortality or neurological outcomes in phase II clinical trials in adults and children respectively 12,13 , these benefits were not translated into improved clinical outcomes (mortality or neurological deficits) in a recent larger clinical trial 16

Isothiocyanates are antimicrobial volatiles produced from glucosinolates by myrosinase enzymes (Bones and Rossiter, AbGst1 was up-regulated in planta during infection suggesting the potential involvement of this enzyme in isothiocyanate detoxification mechanisms during host plant infection (Sellam et al., 2006, 2007)

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