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[2] The combined activation of these receptors results in improved glycaemic control and significant reductions in body weight, making Mounjaro an effective option for individuals with type 2 diabetes who also struggle with obesity

The neuroprotective effects are linked to the activation of the cAMP/PKA/pCREB pathway [45]

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In uno studio del 2021 pubblicato sul New England Journal of Medicine, i partecipanti trattati con semaglutide hanno perso in media circa il 15% del loro peso corporeo, rispetto a una perdita del 2,4% nel gruppo placebo