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This connection is not always obvious but is critically important for researchers trying to optimize their tirzepatide dosing protocols
Marsha Novick: Mild nausea, constipation, diarrhea, fatigue, and low appetite are fairly common with GLP-1 medications like semaglutide (Wegovy) and tirzepatide (Zepbound), especially in the first few days after an injection or after a dose increase
Gum disease has been linked to heart disease, diabetes complications, and respiratory issues
In a 48-week phase 2 trial published in The New England Journal of Medicine , adults with obesity (without type 2 diabetes) receiving once-weekly subcutaneous retatrutide at the 12 mg amount achieved a least-squares mean body weight reduction of 24.2%, compared with 2.1% in the placebo group [1]
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