S1 nerve compression causes pain down the back of the leg to the heel, with potential weakness in plantar flexion (pushing off with the toes)
(4) Blood Pressure (3) In blood pressure studies, compared with l-arginine, pentadecapeptide BPC 157 (without effect on basal normal values) had both a mimicking effect (impaired l-NAME-blood pressure increase, when applied prophylactically and decreased already raised l-NAME values, given at the time of the maximal l-NAME-blood pressure increase (i.e., 10 min after l-NAME)) and preventive activity (l-arginine-induced moderate blood pressure decrease was prevented by BPC 157 pretreatment)
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[3] For researchers who are not peptide chemists, these structural details can be summarized in a simpler way: BPC-157 is a small, linear, water-compatible synthetic peptide with a chemically simple sequence and a biologically complex research profile in published model systems