Brain Behav Immun 55:8292 Shan Y, Tan S, Lin Y, Liao S, Zhang B, Chen X, Wang J, Deng Z, Zeng Q, Zhang L, Wang Y, Hu XQ, Qiu W, Peng L, Lu ZQ (2019) The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke
Nonetheless, the mechanistic alignment between these pathways provides a biologically plausible rationale for future investigationparticularly in the context of dementia prevention, where upstream metabolic and vascular interventions may offer greater leverage than late-stage amyloid-targeted approaches
In this pilot study, 20 (1:1) participants with obesity in the GLP-1RA or control group consumed a challenge dose of alcohol, and we measured breath alcohol (BrAC) and the subjective effects of alcohol
BPC-157: the gastric-derived pentadecapeptide BPC-157 (Body Protection Compound-157) is a stable synthetic pentadecapeptide of 15 amino acids, originally isolated from a larger protective protein found in gastric juice
Tirzepatide is a dual GIP/GLP-1 receptor agonist, the first drug in its class