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Acetyl-CoA then enters the CAC, and through oxidative phosphorylation, it produces 22 ATP molecules per molecule of acetyl-CoA
doi:10.1016/j.jsmc.2023.05.008
In the SURMOUNT-5 trial, tirzepatide produced an average weight reduction of 20.2% (about 50 lbs) over 72 weeks, compared with 13.7% (about 33 lbs) for injectable semaglutide
The graphical abstract was created using BioRender
PMID: 29704637
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