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It also helps keep tight junctions together, preventing bacteria and toxins from slipping out and playing a core role in your intestinal permeability.28 Probiotics Your gut microbiome is made of billions of good bacteria that help fight off harmful bacteria, send food from your stomach to your intestines, and perform a host of other protective functions

Local and systemic effects of bioactive food ingredients: is there a role for functional foods to prime the gut for resilience

Mold spores that enter the body through other routes may also affect the gastrointestinal tract

Biochem Biophys Res Commun 405 , 173179, doi: 10.1016/j.bbrc.2011.01.002 (2011)

This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin