Treatment response depends on deficiency severity, route of administration, underlying cause, patient age, concurrent medical conditions, and medication interactions
High-quality randomized trials focused specifically on weight outcomes in non-deficient populations would clarify these uncertainties
Individuals with less adipose tissue have fewer fat cells available for lipolysis, and the substrate for the enzyme cascade diminishes
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Compared with bariatric surgery, they are non-invasive with no recovery time and nothing close to the outcome