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If reconstituted, follow lab SOP for temperature and stability Handling: Use appropriate personal protective equipment

This table assumes a standard reconstitution of a 5 mg vial with 2 mL of Bacteriostatic Water , resulting in a concentration of 2,500 mcg/mL

The immune system then mounts a defense, only this defense goes overboard and causes a bigger reaction than what is considered normal

[13] DSS Model Results : Weight loss significantly reduced at day 8 Myeloperoxidase activity (neutrophil marker) dropped 50% Prevented colon weight increase and length decrease IL-6 and IL-12 mRNA expression significantly reduced Histology showed less inflammation, reduced cell damage, fewer inflammatory cells in tissue layers TNBS Model Results (more acute inflammation): Weight loss reduced within 1-2 days post-TNBS Colonic MPO activity decreased 30% Prevented TNBS-induced colon shortening Broad cytokine suppression: IL-1, IL-6, TNF-, IFN- mRNA all reduced KPV didnt affect inflammatory markers in healthy mice

Injections bypass that step, so more B12 becomes available to tissues