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reduced abundance of this bacterium significantly correlates with diminished mucus layer thickness and heightened pro-inflammatory states (Ji et al., 2023)
The manipulation included disrupting the precursor degradation pathways ( tnaA and sdaA ), eliminating l-glutathione degradation ( ggt and pepT ), and manipulating the intracellular ATP level (disruption of glgB )
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GLP-1 is produced via the proteolytic cleavage of proglucagon
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