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Skeletal muscle injury represents another notable application domain

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Impure peptide preparations can introduce experimental confounders, as degradation products or synthesis byproducts may have their own biological activities or interfere with receptor binding assays

Cooreman A, Van Campenhout R, Ballet S, Annaert P, Van Den Bossche B, Colle I, Cogliati B, Vinken M

Studies examining HIV-1-associated encephalitis brain tissue using immunohistochemistry have shown that occludin and ZO-1 immunoreactivity is fragmented or completely absent in vessels of the subcortical white matter, basal ganglia, and, to a lesser extent, cortical gray matter