Postmenopausal women lost about 35% more weight when using menopausal hormone therapy alongside tirzepatide a GLP-1-based, Food and Drug Administration-approved drug for the overweight and obese compared to those taking the drug alone, according to a Mayo Clinic study
A subgroup analysis also showed a reduction in the number of cigarettes smoked per day among those individuals with alcohol use disorder who were also smokers
Eli Lilly and Company still owns the current narrative with #Zepbounds surge, and its own oral GLP-1 (#orforglipron) is in the race, but Novo just moved first in oral obesity
Reported side effects Nausea (dose-dependent, more common at higher doses) Facial flushing and increased skin warmth Reduced appetite and mild fatigue Spontaneous erections or increased libido in men Injection site reactions (redness, mild stinging) Changes in existing moles Transient increases in heart rate and blood pressure Storage Lyophilised (unmixed) Freeze at -20 C (-4 F) or below, in dry, dark conditions
Theres a new path to weight loss the GLP-1 pill