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Ensure adequate fluid intake and contact your GP if symptoms are severe or prolonged Changes in mood or mental health : Whilst sertraline treats depression and anxiety, any worsening of mental health symptoms, emergence of suicidal thoughts, or unusual behavioural changes should be reported immediately Appetite changes : Significant loss of appetite or difficulty eating adequate nutrition requires medical review Signs of pancreatitis : Severe abdominal pain radiating to the back, nausea, and vomiting warrant urgent medical assessment, as GLP-1 agonists carry a small risk of pancreatitis [1] [5] Gallbladder problems : Wegovy and rapid weight loss can increase the risk of gallstones and gallbladder inflammation
For these protocols, less water (1 mL) keeps injection volumes manageable
It summarizes published pharmacology, clinical-trial dosing context, and common protocol planning patterns
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