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Lastly, most murine models of obesity also inevitably develop diabetes and thus limit the possibility to investigate the exclusive role of obesity in HFpEF pathogenesis
In contrast, the damage to the GPX4/GSH system caused by IIRI was reversed after metformin treatment, as shown by increases in GPX4, SLC7A11, and GSH
Calling it GLP-3 may be convenient for search and marketing, but it is less precise
There is high-quality evidence to support their use in outpatients with diabetes, heart failure, and chronic kidney disease, and there is some potential benefit for patients with myocardial infarction, Tavares and his team noted
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