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Intraneuronal A was detected at 2 months, progressing to intraneuronal lysosomal accumulation of C-terminal fragments (CTFs) and lysosomal abnormalities by 12 months (Gandy et al., 2010
Li, D., Yang, Y., Li, R., Huang, L., Wang, Z., Deng, Q., & Dong, S
The retinol dehydrogenases that have been shown to be involved in retinaldehyde and retinol interconversions are members of the short-chain dehydrogenase/reductase (SDR) superfamily of enzymes
Biochem Biophys Acta 1830:33173328 Schulz JB, Lindenau J, Seyfried J, Dichgans J (2000) Glutathione, oxidative stress and neurodegeneration
& Sakai, Y
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