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Because NNMT consumes both nicotinamide and SAM, inhibiting the enzyme may alter intracellular 1-MNA, NAD + , SAM, and SAH levels under some experimental conditions

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Dependence of cathepsin L-induced coronary endothelial dysfunction upon activation of [PMID: 19345232] Laboratory literature summary: Dependence of cathepsin L-induced coronary endothelial dysfunction upon activation of NAD(P)H oxidase