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There are cumulating data on reduced GSH levels and the consequent increased susceptibility to oxidative stress in many human diseases, contributing to the onset and worsening of these conditions

After 48 h, biofilms were washed once with 1 PBS followed by treatment with different enzyme solutions prepared in 1 PBS, pH 7.4, including: 5, 10, 20, and 40U DNase-I, 100, 200, 500 and 1000 g/ml amylase and 50, 100, 200 and 500 g/ml Proteinase K, for 24 h, at 37C and 150 rpm, the control was treated with 1 PBS alone

For this reason, acetaminophen is one of the drugs that most commonly cause predictable liver damage (Budnitz et al

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M., Muranen, T., Sharfi, H., Sasaki, A