Considering the significant curative, anti-irritant, anti-inflammatory, antioxidant, immunomodulatory, and skin regenerative properties of thermal water, it can be used as a whole as well as its active ingredients in different topical formulations as therapeutic agents and cosmetics is justified
214,215,216,217 Additionally, sensory neurons in the dorsal root ganglia (DRG) exhibit altered phenotypes, such as reduced neurofilament synthesis, endoplasmic reticulum stress, and changes in key plasticity molecules, such as growth-associated protein 43 (GAP43) and heat shock proteins, leading to mitochondrial dysfunction and loss of peripheral nerve function
The graphic below depicts how specific triggers can lead to certain clinical manifestations, symptoms, and ultimately, autoimmunity
Use3-5 drops on the face and gently massage until fully absorbed
The impact of psychiatric comorbidity on Parkinson's disease outcomes: a systematic review and meta-analysis