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2021), though long-term use should be monitored to avoid nutritional deficiencies
The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta-3 AR knock-out mice
The compound consists of glycyl-L-histidyl-L-lysine sequence chelated with copper, showing unique binding properties in laboratory studies
However, the predominance of rodent studies raises questions about translatability to human pathophysiology and therapeutic responses
Abbreviations ALT: Alanine aminotransferase AST: Aspartate aminotransferase BMI: Body mass index CAP: Controlled attenuation parameter FBS: Fasting blood sugar HbA1c: hemoglobin A1c HDL: High-density lipoprotein IRI: Immunoreactive insulin LDL: Low-density lipoprotein LSM: Liver stiffness measurement NAFLD: Nonalcoholic fatty liver disease NASH: Nonalcoholic steatohepatitis NEFA: Non-esterified fatty acid UMIN: University Hospital Medical Information Network VCTE: Vibration-controlled transient elastography References Day CP
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