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To help manage stress, practice relaxation techniques like deep breathing or meditation, and help your body recover and repair with at least 79 hours of sleep each night

10.1038/s41568-020-0273-y 142 LeoneR

Int J Clin Pract 70:450461 Abdalla MA, Shah N, Deshmukh H et al (2022) Impact of Metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials

The same thing happens in your body

If your eGFR (estimated glomerular filtration rate, a measure of kidney function) is under 30, it indicates kidney problems and means you should talk to your doctor immediately