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The STEP clinical trials demonstrated an average weight reduction of 14.9% over 68 weeks at the 2.4mg dose
In a study evaluating calcium supplementation over six weeks in high-risk pregnant women, improvements in antioxidant activity, modulation of the purinergic system, and reductions in inflammatory cytokines were observed, suggesting a potential adjunctive benefit of calcium in modulating OS-related pathways 43
The medication's effect on gastric motility means that larger meals or foods that typically trigger reflux (such as fatty foods, caffeine, alcohol, or spicy dishes) may be more likely to cause discomfort
Retrieved December 16, 2020
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