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It is widely used in pharmaceuticals, nutraceuticals, and cosmetic formulations for its antioxidant, detoxifying, and skin-brightening properties
Allosteric (off active site) activators were reported in the literature as early as the mid-2000s, but they had poor potency, poor pharmacokinetics, species-selective activity (human but not rodent), and none made it close to the clinic
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Regular use helps improve physical performance, supports heart health, and promotes overall wellbeing
[5] In Latin America, about 40 percent are estimated to be affected, and this may be as high as 80 percent in parts of Africa and Asia
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