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Before starting Wegovy , discuss: Your complete medical history, including thyroid disorders, pancreatitis, kidney disease, or diabetic complications All current medications, including over-the-counter medicines, supplements, and herbal products Any history of eating disorders or mental health conditions Pregnancy plans, as Wegovy should be discontinued at least 2 months before conception During treatment , seek medical advice if you experience: Severe or persistent abdominal pain , especially if accompanied by vomitingthis may indicate pancreatitis and requires urgent assessment (call 999 or attend A&E if severe) Signs of gallbladder problems : pain in the right upper abdomen, yellowing of skin or eyes, fever Symptoms of dehydration : reduced urination, dizziness, dry mouth, particularly if experiencing severe vomiting or diarrhoea Hypoglycaemia symptoms (if diabetic): shakiness, sweating, confusion, rapid heartbeat Changes in vision or eye pain Neck lump, difficulty swallowing, persistent hoarseness, or breathing difficulties Persistent side effects that significantly affect quality of life For urgent but non-emergency concerns, contact NHS 111 for advice

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K., Nair, S., Wile, D

Because the model was applied to evaluate the risk of first MACE in participants with different eGFR and UACR values, the subgroups eGFR 60 mL/min/1.73 m 2 (normal or mildly reduced kidney function) and UACR 300 mg/g subgroups, respectively, had an eGFR 300 mg/g were 1.53 [1.14;2.04] and 2.52 [1.84;3.42] compared with the UACR 300 mg/g: 2.37 [1.70;3.27]