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Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Mounjaro) and chronic weight management (Zepbound) in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, as an adjunct to diet and physical activity

As with any new medication, patients and healthcare providers naturally question potential side effects, including whether Zepbound causes sexual dysfunction

In comparison with controls, complex I activity has been increased from 16 to 47% upon high dose riboflavin therapy (43)

Novo Nordisk leads with Ozempic, which commands nearly one-third of the market ( 31.5% ), followed by Eli Lillys Mounjaro at 23.4%