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- People with significant liver disease (the 9-month monkey toxicology study showed dose-dependent periportal vacuolation in hepatocytes that the FDA flagged as a possible safety signal)
The patient requires a structured loading-dose schedule followed by ongoing injections
ISBN 978-0-7876-1013-5
But, if either substances are pushed too quickly the resulting damage to the tissue can cause a nasty charley horse like pain that can persist for hours or days
2000;279(3):E501, 7
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