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People undergoing chemotherapy or radiation therapy : These treatments can cause oxidative damage and deplete glutathione levels, making it harder for the body to recover
The neurological aspects of the disease are thought to arise from the accumulation of methylmalonyl- CoA due to the requirement of B 12 as a cofactor to the enzyme methylmalonyl-CoA mutase
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Conclusion: Implementing Evidence-Based B12 Therapy for Optimal Outcomes Using evidence-based guidelines for vitamin B12 therapy is key for the best patient results
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