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Different from PCD, secondary carnitine deficiency (SCD) is mostly caused by drugs (such as valproic acid, anticancer drugs, omeprazole, amphoteric drugs, etc.) or diseases (such as fatty acid oxidation disorder, organic acidemia, etc.) (1)

For example, one clinical review noted that orally administered glutathione cannot be relied upon for therapeutic purposes, whereas IV or certain novel routes are needed for significant increases

J Exp Bot 55:18511859 Gonzalez-Reyes JA, Hidalgo A, Caler JA, Palos R, Navas P (1994) Nutrient-uptake changes in ascorbate free radical-stimulated onion roots

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