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Polymorphism of glutathione S-transferase M3: interaction with glutathione [PMID: 23885907] Laboratory literature summary: Polymorphism of glutathione S-transferase M3: interaction with glutathione S-transferase M1 and lung oncology research models susceptibility

Kim Y, et al

Administered intravenously, glutathione reaches peak plasma concentration within minutes, distributing to skin, liver, immune cells, and all major organ systems simultaneously

PMID: 26580671

While limited research exists on cytotoxic T cells (Tc) in MASLD, studies in other immune disorders suggest SIRT1 regulates Tc function through T cell receptor expression and deacetylation of effector proteins such as perforin and granzyme