Summary Keywords abiotic stress, arsenic, detoxification, glutathione, heavy metals, oxidative stress Citation Kumar S and Trivedi PK (2018) Glutathione S-Transferases: Role in Combating Abiotic Stresses Including Arsenic Detoxification in Plants
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Thus, in an environment of metabolic overload and insulin resistance, -cells initially activate compensatory pathways to improve insulin secretion, but they eventually initiate several pathological programs that synergistically promote -cell dysfunction and apoptosis [20]
Future multicenter studies with extended follow-ups are needed to validate and expand this model
JCSM Rapid Communications (2020) 10