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Effect of intensive lifestyle intervention on bodyweight and glycaemia in early type 2 diabetes (DIADEM-I): an open-label, parallel-group, randomised controlled trial
These shifts tend to even out with time
Cardiovascular outcomes studies in people with T2D and high cardiovascular risk have shown that DPP4i have an overall cardio-neutral profile 32,33,34,35,36,37 , while GLP1-RAs were associated with decreased all-cause mortality and major adverse cardiovascular events (MACE) 38
5,7 Sleep and circadian rhythm Adequate sleep is essential for effective weight management, as it regulates appetite-related hormones, supports metabolic function, and promotes energy utilization
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